Finally, if ACE2 and Ang II clearly play a role in the thrombosis and cardiovascular complications following the COVID-19 mRNA vaccine, it has also been suggested that another physiopathological mechanism can sometimes trigger the cerebral venous sinus thrombosis (CVST) and cerebral venous thrombosis observed after vaccination with an adenoviral-vector-based vaccine [105]. Here, ACE2 is linked to deep vein thrombosis.