IARS1 and cancer: Concerning the inflammatory cell infiltrates, nuclear IRS in the CIN1 (p < 0.001), CIN2 (p = 0.03), CIN3 (p = 0.017), and cancer (0.0288) groups was lower than that in the control, whereas the cytoplasmic IRS of the CIN1 group had lower IRS compared to the control (p = 0.0047), CIN2 (p = 0.001), and CIN3 (p = 0.0192) groups.