NLRP3 and cryopyrin-associated periodic syndrome: The NLRP3 inflammasome is essential for host immune defense against pathogen invasion, such as bacterial, fungal, and viral infections, and homeostasis, but when the regulation is disordered, it contributes to the pathogenesis of a variety of inflammatory disorders, such as gout, cryopyrin-associated periodic syndromes (CAPS), diabetes, Alzheimer’s disease, and atherosclerosis [19,20,21].