The animal model found that aP cationic lipid nanoparticle vaccines induced systemic and mucosal immune responses (Th1-type responses, IgG2a, and IgA antibody responses) after intranasal delivery in immunized mice, showed promising results, and could be used as a potential formulation for intranasal administration of pertussis vaccines [91]. The gene discussed is CD79A; the disease is pertussis.