Increased levels of cardiovascular disease markers in human serum, which are creatinine kinase MB subform (CK-MB), Troponin I (cTnI), Troponin T (cTnT), Myoglobin, C-reactive protein (CRP), Myeloperoxidase (MPO), heart fatty acid binding protein (H-FABP), and homocysteine (Hcy), are a reliable symptom associated with cardiovascular disease patients. Here, TNNI3 is linked to cardiovascular disorder.