TTR and obesity due to melanocortin 4 receptor deficiency: On the other hand, in the pharmaceutical industry, health benefits are sought in various diseases such as cancer [157,158,159], stress, antisicosis [160], obesity [161,162], diabetes, antidiabetic, hypolipidemic, anti-inflammatory [163], tuberculosis [164], the polyneuropathy of hereditary transthyretin [165], and acne [166].