CFTR and cystic fibrosis: Consequently, combination therapies of CFTR correctors and potentiators are available to CF patients, such as lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor, while ivacaftor is the CFTR potentiator that increases CFTR opening probability, and others are correctors that increase the amount of CFTR protein on the cell surface [63].