APC and glioblastoma: Based on this report, Yang and co-workers investigated GBM orthotopic xenografts and revealed that p65 (also named RELA), DNM3 (Dynamin 3) and CD117 (KIT proto-oncogene receptor tyrosine kinase) expression levels increased, whereas TP53, APC (Adenomatous polyposis coli) and PTEN decreased in tumors and blood exosomes [164].