For primary cutaneous CD30+ T-cell lymphoproliferative disorders, which encompass primary cutaneous anaplastic large-cell lymphoma (ALCL) and lymphomatoid papulosis (LyP), involved-site radiation therapy or surgical excision are options for solitary or grouped lesions of primary cutaneous ALCL, while topical steroids or phototherapy are suitable for limited lesions of LyP. The gene discussed is TNFRSF8; the disease is anaplastic large cell lymphoma.