Statistical analysis revealed that the high immunohistochemical expression of Gpx-1 was significantly correlated with tumour histological grade (p < 0.001, Chi2test), depth of invasion (p < 0.001, Chi2test), angioinvasion (p < 0.001, Chi2test), and PCNA immunohistochemical expression (p < 0.001, Chi2test). This evidence concerns the gene PCNA and neoplasm.