AKT1 and amelogenesis imperfecta type 1G: The effects of DHQ were inhibited by PI3K/AKT inhibitor LY294002, which suggest that DHQ alleviated MIRI at a dose of 2.5, 5, 10, 20, 40, and 80 μM via activation of PI3K/AKT pathway, which subsequently reduced oxidative stress and apoptosis induced by ERS [31].