RYK and neoplasm: After performing multivariate analyses, neoplasm histologic grade (G3 vs. G2, HR = 3.72; 95% CI, 2.02–6.83, p < 0.001) and RYK expression status (high vs. low, HR = 0.44; 95% CI, 0.22–0.91, p = 0.027) (Figure 4a) were significant risk factors for OS in this patient group.