Other studies have shown that AVN 2c plays a role in protecting the intestine against ovalbumin-induced allergy via mediating the Hsp70-NF-κB signaling pathway [34], as well as its ability to protect against pyroptosis through ROS-induced mitochondrial damage via PI3K ubiquitination and phosphorylation in pediatric pneumonia [35], demonstrating its anti-inflammatory effect. The gene discussed is NFKB1; the disease is allergic disease.