AVP and neoplasm: Figure 3 displays the images and MTRasym spectra for two representative mice. As can be seen, an increase in CEST MRI contrast was observed in all mice with an average difference in CEST MRI tumor contrast at Δω = 4.4 ppm post minus pre-injection at (MTRasym) = 1.5%, rmsd = 0.3 for n = 5 mice at 34 min post-injection. These data indicate that ADH can be used as CEST contrast agent for depicting perfusion differences found in tumor tissue.