Data from The Cancer Genome Atlas (TCGA) show the presence of signature mutations (C-to-T transitions or C-to-G transversions in TCX sequences, where the underlined base is the mutated base, and X can be any base) [41] attributed to APOBEC3A (A3A) and APOBEC3B (A3B) activity in breast, bladder, lung, head and neck, and cervical cancers [4,42]. This evidence concerns the gene APOBEC3B and cervical carcinoma.