BCS2 group progressively shorter OSNAT was not the 3y OS independent prognostic factor after radical gastrectomy.BCS2 group associated with lower BMI and higher NRS2002 score.Body composition does not affect post-surgery complications.BCS2 group worse preoperative markers (hypoalbuminemia, lower prealbumin and IGF-1 levels). This evidence concerns the gene TTR and Hypoalbuminemia.