Likewise, the intake of turmeric capsules containing 22.1 mg of curcumin (three times a day for eight weeks) resulted in a significant decrease in CRP, IL-6 and TNF-α levels [49], as well as increased levels of antioxidants such as GPX, glutathione reductase (GR) and CAT [22,65] in HD patients, without adverse effects (Table 2). This evidence concerns the gene TNF and Huntington disease.