In addition, rosmarinic acid specifically inhibits the P-protein of hepatitis B virus [218], RA could influence the early state of viral infection and directly affect viral particles by affecting virus-P-selectin glycoprotein ligand-1 (PSGL1) interactions with heparan sulfate substance without affecting virus–scavenger receptor B2 (SCARB2) interactions [196]. The gene discussed is SELPLG; the disease is viral infectious disease.