NFKB1 and rheumatoid arthritis: Results showed that NF-κB p65 (RELA) could be a critical target for anti-inflammation and anti-RA (Figure 7), and LB exhibited a better interaction than Helenalin (Figure 8), a sesquiterpene lactone anti-inflammatory inhibitor from Arnica by selectively inhibiting NF-κB p65 [29].