At the absolute quantification level, the five most abundant proteins, i.e., HSPA8 (104.4 ± 67.3 fmol/μg), CD63 (18.9 ± 8.6 fmol/μg), CDC42 (7.4 ± 2.9 fmol/μg), SLC2A1 (7.4 ± 3.6 fmol/μg), and CD81 (5.6 ± 4.7 fmol/μg), were overrepresented in WhL samples derived from CRC cell lines (Figure S2). The gene discussed is CD81; the disease is colorectal carcinoma.