The transmembrane protein CD47, also known as an integrin-associated protein (IAP) and served as a self-recognition marker [1], is ubiquitously expressed in human cells, various hematologic and solid tumors [2], and involved in cell apoptosis, proliferation, adhesion, migration and tumor development, as well as immune responses [3,4,5,6,7]. The gene discussed is CD47; the disease is neoplasm.