Aucubin also prevented the elevation of MMP-9, MCP-1, apoC-III, ICAM-1, VCAM-1, TNF-α, IL-1β, and IL-6 levels after stimulation by apoC-III in 3T3-L1 cells and in mice with tyloxapol-induced nonalcoholic fatty liver disease (NAFLD) [62]. Here, CCL2 is linked to metabolic dysfunction-associated steatotic liver disease.