As the main mechanism of action, the extract suppressed gluconeogenesis by inhibition (almost 100%) of the enzymes glucose-6-phosphatase (G6Pase) and fructose-1,6-bisphosphatase (FBPase), which is the altered pathway that causes fasting and postprandial hyperglycemia in patients with T2D; the extract also reduced the activity of a-glucosidases by 32%. This evidence concerns the gene G6PC1 and type 2 diabetes mellitus.