HMGCR and hydrops fetalis: Compared with the NC group, the mRNA expressions of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR), low-density lipoprotein receptor (LDLR), and bile acid transporter (ASBT) in the liver in the HF and HF + LP groups were significantly decreased (p < 0.05), while the mRNA expression of cholesterol 7a-hydroxylase (CYP7A1) was significantly increased (p < 0.05) (Figure 2B).