Compared with the HF group, the mRNA expression levels of IL-1β and TNF-α in the spleen in the HF-LP group were significantly decreased (p < 0.05), while the mRNA expression of IL-10 was significantly increased (p < 0.05) and the mRNA expression of IL-4 was not significantly changed (p > 0.05) (Figure 2A). The gene discussed is IL1B; the disease is hydrops fetalis.