cytotoxic to 293, B16F10, BJAB, and HCT116 tumor cells (in vitro; doses 15.0–50 μg/mL)increased expression of caspase-3 and caspase-8 in HCT116 (human colon cancer cells) and tumor cell apoptosis. The gene discussed is CASP3; the disease is malignant colon neoplasm.