treatment of neurodegenerative diseases by reducing cell apoptosis as a result of:○decrease in acetylation of p53 lysine 382,○increase in the potential of the mitochondrial membrane,○reduction of the BAX/Bcl-2 ratioreduction of cleavage of PARP [Poly (ADP-ribose) polymerase]. The gene discussed is BCL2; the disease is neurodegenerative disease.