Patients with high serum AFP levels had lower ALB (p = 0.004), higher GLB (p = 0.002), higher ALT (p < 0.001), higher AST (p < 0.001), higher TBIL (p < 0.001), higher APRI scores (p < 0.001), higher FIB-4 scores (p < 0.001), and a higher proportion of advanced fibrosis (≥S3) (p < 0.001) and cirrhosis (≥S4) (p < 0.001) compared to patients with normal serum AFP levels. This evidence concerns the gene GPT and Cirrhosis.