PKD1 and Renal cyst: They confirmed that miR-192-5p, miR-194-5p, miR-30a-5p, miR-30d-5p, and miR-30e-5p were significantly downregulated in the urine exosomes in both murine and human PKD1 cystic kidneys, and all were significantly correlated with baseline eGFR and ultrasound-determined mean kidney length.