The expression of HSPB1 in the tumour tissues of breast invasive carcinoma (BRCA), cholangiocarcinoma (CHOL), oesophageal carcinoma (ESCA), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) was significantly higher than in the normal tissues (p < 0.05). Here, HSPB1 is linked to chromophobe renal cell carcinoma.