HSPB1 and rectum adenocarcinoma: As presented in Figure 7, high expression of HSPB1 was significantly associated with poorer overall survival (OS) in colon adenocarcinoma (COAD) (p = 0.027), rectum adenocarcinoma (READ) (p = 0.027), glioblastoma multiforme (GBM) (p = 0.019), brain lower-grade glioma (LGG) (p < 0.001), liver hepatocellular carcinoma (LIHC) (p = 0.035), malignant mesothelioma (MESO) (p = 0.005) and skin cutaneous melanoma (SKCM) (p = 0.013).