TERT mutations have been detected in a wide range of urothelial pathologies, including benign urothelial proliferations and tumor-like lesions, benign urothelial neoplasms, premalignant and putative precursor lesions, urothelial carcinoma and its subtypes across gender, tumor grade, and stage, and nonurothelial malignancies [25]. The gene discussed is TERT; the disease is neoplasm.