Several studies reported that 97% of patients with IgA- or IgG-type MM have an altered iHLC/ uHLC ratio at diagnosis [41,42] and that there is an association between the presence and diagnosis of suppression of uninvolved immunoglobulin (uHLC) and shorter survival [33,42], as well as a higher incidence of infection [33,42,43,44]. Here, CD79A is linked to Miyoshi myopathy.