MMP8 and periodontal disorder: Salivary biomarkers, such as salivary IgA and IgG against the pathogens Porphyromonas gingivalis and Treponema Denticola, salivary IgG against Aggregatibacter Actinomycetemcomitans, MIP-1a (Macrophage Inflammatory Protein-1a), interleukin 1β, (IL-1β), interleukin 6 (IL-6), Matrix metalloproteinase-8 (MMP-8), and Prostaglandin E2 (PGE2), are used to assess susceptibility to develop more or less severe periodontal diseases [42,43,44,45,46,47,48,49].