The goal of the study by Rakic et al. was to assess the diagnostic efficacy of osteoprotegerin (OPG) and nuclear factor kappa-B receptor activator (RANKL) in the diagnosis of peri-implantitis (PIMP) and peri-implant mucositis (PIM) [75]. This evidence concerns the gene TNFRSF11B and Peri-Implantitis.