The TC and TT genotypes of the VWF gene were found to be related with risk and susceptibility to stroke in the codominant model, with OR 8.12 (95%) CI = (4.1752 to 15.8113), RR = 2.58 (1.859 to 3.588) and p < 0.0001, while the VWF rs61748511 CC genotype was significantly associated with stroke risk, with OR 26.1 (95%) CI = (5.53 to 124.52), RR = 6.61 (1.79 to 24.41) and p < 0.0001, (Table 4). The gene discussed is VWF; the disease is stroke disorder.