In the current study, we examined the associations of the GSTs SNPs (Mu 1 (GSTM1) and Theta 1 (GSTT1)), TNF-alpha SNP rs1800629 G > A SNP and VWF SNP rs61748511 T  > C (Figure 1) with stroke in the Tabuk population. This evidence concerns the gene GSTM1 and Stroke.