In addition, researchers found that two groups of pro-inflammatory macrophages with high expression of CXCL9 and CXCL10 were enriched in the tumor microenvironment of response patients, and there was a significant positive correlation between these two groups of pro-inflammatory macrophages and CXCL13+ T cells [45,46]. The gene discussed is CXCL13; the disease is neoplasm.