GPX4 and hepatocellular carcinoma: In comparison to the control group, the ferroptosis-related proteins COX2, NRF2, and CD71 were upregulated, and GPX4, xCT, FTH1, and FLCA were downregulated dose-dependently in the uridine-treated group (Figure 5C), indicating that uridine could inhibit HCC tumor growth in vivo via the induction of ferroptosis.