After adjusting for MR etiology, female gender (OR: 0.67; 95% CI: 0.46–0.97; p = 0.038), NYHA class (OR: 1.59; 95% CI: 1.21–2.1; p = 0.004), troponin (OR: 1.92; 95% CI: 1.32–2.78; p < 0.001) and NT-proBNP (OR: 1.73; 95% CI: 1.08–2.81; p = 0.022) were identified as independent endpoint predictors instead. Here, NPPB is linked to miotic rate.