The HPA reported that family members encoded by the ESRR genes function as transcriptional activators of DNA cytosine-5-methyltransferases 1 (DNMT1) expression by binding directly to its response elements in DNMT1 promoters, thereby modulating cell proliferation and estrogen signaling in breast cancer (https://www.proteinatlas.org/ENSG00000196482-ESRRG accessed on 1 October 2022). Here, ESRRG is linked to breast cancer.