The O-methylated flavonol rhamnetin and the natural flavonoid cirsiliol overcame radioresistance via the downregulation of Notch1, Ciap1, Ciap2, survivin, vimentin, and fibronectin and the up-regulation of E-cadherin in radio-exposed non-small cell lung cancer cells [58]. Here, BIRC5 is linked to non-small cell lung carcinoma.