Next, we analyzed the regulation of genes involved in EMT (β-catenin, L1CAM, SNAIL2), stemness (Nestin, Oct4, Nanog, Musashi, Pax6), angiogenesis (VEGFa), and cell cycle regulation (p21, p53) in surviving PCa cells treated with TMZ+AT101/AT101, Torin2, or combined Torin2 and TMZ+AT101/AT101 (Figure 5C). This evidence concerns the gene PAX6 and posterior cortical atrophy.