CCP110 and schizophrenia: Studies have shown that centriolar coiled-coil protein 110 (CCP110), cytoskeleton-associated protein 5 (CKAP5), disrupted in schizophrenia 1 (DISC1), and transforming acidic coiled-coil containing protein 3 (TACC3) are essential for oocyte microtubule polymerization and spindle assembly.