TGFB1 and Hepatic fibrosis: In liver fibrosis, WNT/β-catenin also regulates the expression of vimentin, collagen 1, and fibronectin in hepatic stellate cells induced by TGF-β [132]; however, recently, there seems to be a turnaround derived from the demonstration that constitutively active canonical Wnt/β-catenin signalling confers tolerogenicity to hepatic dendritic cells under steady-state conditions and, therefore, deficiency of canonical Wnt/β-catenin signalling in these cells seems to be responsible for the triggering of autoimmune hepatitis [133].