In RA, the link between TGF-β expression and EMT was recently confirmed through the observation that the synovial membrane or synovial fluid showed increased levels of TGF-β [37]; furthermore, EMT features, such as more aggressive and invasive cell phenotypes and resistance to apoptosis, that causes pannus tissue invasion and destruction in RA were detected [38]. The gene discussed is TGFB1; the disease is rheumatoid arthritis.