Aberrant STING activation has been associated with certain autoimmune diseases such as systemic lupus erythematosus, inflammatory vasculopathy, rheumatoid arthritis, Aicardi-Goutières, or other less frequent pulmonary and autoinflammatory diseases such as SAVI (STING-Associated Vasculopathy with onset in Infancy). This evidence concerns the gene STING1 and rheumatoid arthritis.