Another article described the safety and efficacy of intracerebral injection of an AAV encoding genes N-sulfoglycosamine sulfohydrolase (SGSH) and sulfatase-modifying factor (SUMF1) in four children with Mucopolysaccharidosis Type IIIA (MPS Type IIIA) disease [42]. The gene discussed is SGSH; the disease is mucopolysaccharidosis type 3A.