MYCN and neuroblastoma: In contrast to the mutually exclusive expression profile of LIG4 with the MYCN oncogene, the increased expression of LIG4 was correlated with the unfavourable prognosis in the 66 and 92 MYCN-amplified neuroblastoma datasets (Tumour Neuroblastoma Kocak-649-custom-ag44kcwolf, raw p = 0.000056 and Bonferroni corrected p = 0.0028, Figure 2B; Tumour Neuroblastoma SEQC-498-RPM-seqcnb1, raw p = 0.0025 and Bonferroni corrected p = 0.194, Figure S2, respectively), suggesting that LIG4 could be involved in an oncogenic potential with relevance to MYCN.