WNT/β-catenin signaling controls cellular signaling cascades, including epidermal growth factor receptor (EGFR), Hippo/YAP, nuclear factor kappa-B (NF-kB), Notch, Sonic Hedgehog, and the PI3K/Akt pathway, which are involved in cancer development [72,73,74]. This evidence concerns the gene AKT1 and cancer.