PPARG and inflammatory bowel disease: Moreover, the administration of the PPAR-γ modulator GED in the animal model of IBD prevented the aberrant activation of all these pathways, endorsing the protective effect of the PPAR-γ on the intestinal mucosa in the context of IBD and widening the role of PPAR-γ as a main orchestrator of the intestinal fitness, being potentially more efficacious than 5-ASA.