Significantly higher in AML-MSC versus R-MSCs 21 proteins (EXT2, ADAMTS2, LOX, LTBP3, RPL7A, NID2, PRKCSH, ARHGDIA, HEL-S-47e, TUBB6, CPQ, PGCP, PGM2, CFAP44, ERP29,HEL-S-107, PSMD6, LGALS1, VTN, PSMB7, PDIA3, CTSL, INHBA, and MFAP5). The gene discussed is ARHGDIA; the disease is acute myeloid leukemia.