Secreted in R-MSCs, not secreted in AML-MSCs: 405 proteins, significant only 3: F10—Coagulation factor X; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va; CTGF—Cellular communication network factor 2; Connective tissue growth factor; Major connective tissue mitoattractant secreted by vascular endothelial cells; LAMA2—Laminin subunit alpha-2; Binding to cells via a high-affinity receptor, laminin is thought to mediate the attachment, migration, and organization of cells. The gene discussed is LAMB2; the disease is acute myeloid leukemia.