Thus, the aim of our study was to study the levels of adipokines (Glucose-dependent insulinotropic polypeptide (GIP), Glucagon-like peptide-1 (GLP-1), Glucagon, Insulin, Leptin, Adiponectin, Adipsin, Lipocalin-2, Resistin), as well as their associations with unstable atherosclerotic plaques in patients with coronary atherosclerosis and abdominal obesity. The gene discussed is GLP1R; the disease is coronary atherosclerosis.