CRB1 and severe early-childhood-onset retinal dystrophy: Another Chinese study [46] on LCA and EOSRD cases lists as the first five most frequently mutated genes AIPL1 (11%), RPGRIP1 (9%), and CEP290, GUCY2D, and RPE65 (each 8%) in the LCA patient group, and RPGR (12%), CRB1, and RPE65 (each 11%), RDH12 (7%), and RP2 (5%) in the EOSRD patient groups.