Interestingly, we found a significant positive correlation between the expression of IL15RA, IL17RC, and IL17RD genes and the invasiveness of cell lines (R = 0.933, p = 0.007; R = 0.872, p = 0.024; and R = 0.938, p = 0.006, respectively, Figure 3), and those three receptor genes displayed significantly increased expression in the selected invasive melanoma cells after culturing with HHSEC-CM as well. Here, IL15RA is linked to melanoma.