Similarly, cell proliferation of transiently transfected HBME cells with the pcDNA3-14 kDa hGH plasmid was significantly reduced by approximately 50% compared to nontransfected cells or cells transfected with an empty pcDNA3 plasmid (Figure 2B), suggesting that 14 kDa hGH suppresses cell proliferation in cancer and endothelial cells. The gene discussed is GH1; the disease is cancer.