Additionally, HBME cells transfected with pcDNA3 containing 14 kDa hGH showed a significant increase to 20% of apoptotic cells compared to 10% in control cells (Figure 3B,D), confirming that 14 kDa hGH induces apoptosis of endothelial and melanoma cells in vitro. The gene discussed is GH1; the disease is melanoma.